勃林格殷格翰制药公司博士后职位——PROTACs开发

川大-灰太狼

勃林格殷格翰制药公司博士后职位

Postdoctoral Scientist (m/f) on new E3 Ligase systems and protein targeting chimeras (PROTACs) - 2 years fixed term contract (optional extension)

工作地点：奥地利维也纳

工作内容：新E3连接酶系统和蛋白质靶向嵌合体（PROTACs）的研发

工作时间：2年

发布时间：2018年8月16日

If you are an enthusiastic, highly motivated and creative postdoctoral scientist, you should join us within the Department of Medicinal Chemistry at Boehringer Ingelheim RCV to drive innovative research in the field of protein targeting chimeras (PROTACs). This project aims to come up with new E3 ligase systems for new and innovative protein degradation systems. The advertised position is part of the global Boehringer Ingelheim Postdoc Programme and we encourage applications from individuals with a strong background and interest in the PROTAC field.

Duties & Responsibilities:

• Working on new innovative and unexplored E3 ligases to develop new PROTAC concepts with full responsibility for the project
• Expression and purification of new E3 systems as well as biophysical and biochemical method development to test these systems in vitro
• Generating prototypes of new PROTAC tools together with Medicinal Chemists
• Present your research at external and internal meetings
• Publish in peer-reviewed journals
• Learn about drug discovery and development
• Leverage collaboration opportunities within Boehringer Ingelheim
• 
  
  
  

Requirements:

• PhD degree with proven scientific track record through high quality scientific publications
• Deep knowledge of E3 ligases and the functional effects of ubiquitination and of protein science in general
• Proven ability to work independently and collaborate in order to achieve objectives, as demonstrated by publications
• Demonstrated problem solving skills and strategic research planning
• Basic knowledge in protein crystallography or electron microscopy is a plus
• Excellent communication, networking and presentation skills, as well as data analysis and data management skills
• A high level of written and verbal English, editing and computer skills including Microsoft Word, Excel, Outlook and PowerPoint
  
• 
  

About Boehringer Ingelheim’s Postdoc Programme:

• The initial appointment is for 2 years fixed term contract with potential for a 1 year extension
• As a Postdoctoral Fellow you will benefit from a fully resourced and fully funded research environment with access to state-of-the-art tools, technologies and equipment
• Embedded in the BI Discovery Research organization, you will benefit from vibrant and regular scientific exchange within BI’s post doc community, including global BI post doc retreats, and with research scientists as well as with academic collaboration partners
• You will be expected to publish your scientific results in peer-reviewed journals and present your data at international conferences
  
• 
  

Your Benefits:

• Staff restaurant
• Pension scheme
• Additional off-days (bridge days)
• Comprehensive health promotion
• Position specific training opportunities
  
• 
  
  

For this position we offer an interesting salary package considering your expertise and personal competencies as well as your professional experience.

Our culture

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment which benefits our employees, patients and communities.

Innovative medicines for people and animals have for more than 130 years been what the research-driven pharmaceutical company Boehringer Ingelheim stands for. Boehringer Ingelheim is one of the pharmaceutical industry’s top 20 companies and to this day remains family-owned. Day by day, some 50,000 employees create value through innovation for the three business areas human pharmaceuticals, animal health and biopharmaceutical contract manufacturing. In 2017, Boehringer Ingelheim achieved net sales of nearly 18.1 billion euros. R&D expenditure, exceeding three billion euros, corresponded to 17.0 per cent of net sales.

For more information please visit https://www.boehringer-ingelheim.com.

Contact

Your HR Recruiting Manager for this Position is Carola Luengo Espinoza.

We invite you to visit our career site! You will find there more interesting information, such as the application process or about our diverse divisions.

博后申请链接：点击进入