Centos6.4下安装Discovery Studio2.55后Zdock运行问题解决！

川大-灰太狼

Centos6.4（ 64位）Linux系统下安装好DS2.55后，运行zdock出现错误。

1. Error while parsing script or executing script outside of subroutines.
   
2. Can't load '/soft/Accelrys/PP7.5/apps/scitegic/dscore/server/lib/libMdmDiscoveryScript.so' for module MdmDiscoveryScript:
   
3. /usr/lib/libfontconfig.so.1: undefined symbol: FT_Select_Size at
   
4. /soft/Accelrys/PP7.5/apps/scitegic/core/packages_linux32/perl/perl-5.8.9/lib/5.8.9/i686-linux-thread-multi/DynaLoader.pm line 226.
   
5. at /soft/Accelrys/PP7.5/apps/scitegic/dscore/lang/perl/Utilities/ConvertToMol2.pm line 15
   
6. Compilation failed in require at /soft/Accelrys/PP7.5/apps/scitegic/dscore/lang/perl/Utilities/ConvertToMol2.pm line 15.
   
7. BEGIN failed--compilation aborted at /soft/Accelrys/PP7.5/apps/scitegic/dscore/lang/perl/Utilities/ConvertToMol2.pm line 15.
   
8. Compilation failed in require at (eval 12) line 4.
   
9. BEGIN failed--compilation aborted at (eval 12) line 4.
   
10. Error calling function
    
11. Error during call to function pilot::setup::scriptingSetup
    
12. PerlScript::HandleError: Pipeline Pilot exception rethrown
    
13. PerlScript::Call: Pipeline Pilot exception rethrown
    
14. CComponentPerlPlugin::onInitialize: Pipeline Pilot exception rethrown
    
15. -> Convert file to mol2 (Perl (on Server)) - error during Initialization phase
    
16. CProtocolBaseImpl::GetNextStartNodeForNewData: Pipeline Pilot exception rethrown
    
17. CProtocolBaseImpl::SetUpComponentStack: Pipeline Pilot exception rethrown
    
18. CProtocolRtc::onProcess: Pipeline Pilot exception rethrown
    
19. CProtocol::onProcess: Pipeline Pilot exception rethrown
    
20. -> Create and Read File (Subprotocol) - error during Data Record Processing phase
    
21. CProtocolStd::onProcess: Pipeline Pilot exception rethrown
    
22. CProtocol::onProcess: Pipeline Pilot exception rethrown
    
23. -> DS Molecule Reader (DS Molecule Reader) - error during Data Record Processing phase
    
24. CProtocolStd::onProcess: Pipeline Pilot exception rethrown
    
25. CProtocol::onProcess: Pipeline Pilot exception rethrown
    
26. CComponentRunner::CallOnProcess: exception caught, calling onFinalize before rethrow
    
27. Protocol Dock Proteins (ZDOCK), user albert: Pipeline Pilot exception caught
    
28. Protocol Dock Proteins (ZDOCK), user albert: Protocol failed: Pipeline Pilot error
    
29. Pipeline Pilot Server version 8.5.0.200

复制代码

解决办法：
1、cd /home/caixin/Accelrys/PipelinePilot/linux_bin/libfreetype.so.6
2、mv libfreetype.so.6 libfreetype.so.6_bak
3、 cp /usr/lib/libfreetype.so.6 libfreetype.so.6

总到来说就是用系统到 libfreetype.so.6 替换DS的PipelinePilot里面的libfreetype.so.6 。

最后Zdock顺利运行，Rdock也顺利运行！

Warlock.Y

:):):):):)